A computational model of the more than 26 million atoms in a DNA-packed viral capsid expands our understanding of virus structure and DNA dynamics, insights that could provide new research avenues and ...
Separating full and empty adeno-associated virus (AAV) capsids during the manufacture of single-gene therapies remains a significant challenge. Ultracentrifugation and anion exchange chromatography ...
Coarse-grained simulations of HK97 genome packaging. A motor protein pushes DNA through a portal into the capsid, where the DNA coils into switchback loops. DNA is colored in order of entry into the ...
Watch this dynamic webinar for valuable insights into characterizing the stability of an engineered adeno-associated virus (AAV) serotype under moderate thermal stress and physiological solution ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results