Since then, many scientists, including Lu, who now leads his own research group at Western University, have shown that PIN1 is overexpressed in different types of cancer and regulates many oncogenes ...

A new study has identified a protein that helps drive bladder cancer by triggering the synthesis of cholesterol via mouse and cell models. Researchers found that a combination therapy of two drugs ...

In a new translational research study published in Cancer Research, investigators at Beth Israel Deaconess Medical Center (BIDMC) explored the potential of statins—commonly used medications for ...

Researchers discover novel targets for bladder cancer therapeutics and demonstrate that a new combination of existing drugs, including statins, blocks tumor growth in mice. Like all cancers, bladder ...

Hopes are high for a powerful new compound aimed at lowering blood fat levels responsible for potentially fatal heart disease. In a recent trial, the oral drug, TLC-2716, lowered blood triglycerides ...