For the first time in humans, researchers have discovered a large chromosomal rearrangement that bears the mark of natural selection, they report in the February issue of Nature Genetics. The ...

For decades, the Y chromosome — one of the two human sex chromosomes — has been notoriously challenging for the genomics community to sequence due to the complexity of its structure. Now, this elusive ...

Chromosomal rearrangements, such as chromosome segment inversions, may affect the epigenetic landscape as well as gene expression. Indeed, different kinds of chromosome segment inversions have been ...

Highly challenging to sequence and long overlooked, the human Y chromosome's contributions to health and disease remain largely unknown. A new paper that presents, for the first time, the complete ...

The human genetic blueprint is deceptively simple. Our genes are tightly wound into 46 X-shaped structures called chromosomes. Crafted by evolution, they carry DNA and replicate when cells divide, ...

Jenny Graves is a Friend of The Conversation. Neanderthals, the closest cousins of modern humans, lived in parts of Europe and Asia until their extinction some 30,000 years ago. Genetic studies are ...

Researchers at deCODE Genetics in Reykjavik, Iceland, have discovered a large chromosomal rearrangement in the human genome that appears to have been selected for in some European populations. 1 The ...