Drug resistance is defined as the lack of expected response to a standard therapeutic dose of a drug or as resistance resulting from biologic changes in the target, as occurs in antibiotic resistance.

Blood clotting disorders can be inherited or acquired and lead to either excessive bleeding or too much clotting.

The ROTEM system is a point‑of‑care device used to help detect, manage and monitor haemostasis associated with high blood loss. The device uses thromboelastometry, a viscoelastometric method, to test ...