C. elegans as a new animal model for treating HBV We are in the process of mapping and cloning the hids genes. We also initiated a large-scale drug screen in C. elegans to isolate compounds that ...
Schematic representation of histone-modifying factor recruitment on cccDNA minichromosomes in relation to viral protein HBx. In the presence of HBx, histone-modifying factors such as p300/CBP, Set1A, ...
This study found that HBV increases sorafenib and regorafenib resistance in HCCs through upregulation of CD133 and activation of the SRC/STAT3 signaling pathway. Our data provide a potentially key ...
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