Many types of cancer are caused by gene mutations in the signalling pathways that control cell growth, such as the hedgehog signalling pathway. A new study from the Karolinska Institutet, published in ...

The Hedgehog (Hh) signalling pathway is a highly conserved mechanism that directs cell fate, patterning and tissue homeostasis throughout embryogenesis and adult life. Signalling is initiated when a ...

A discovery with major implications for cancer treatment has been made by a team of researchers from Rensselaer Polytechnic Institute (RPI), the University of Nebraska Medical Center (UNMC), ...

Genetic experiments integrated with ChIP-sequencing and CRISPR interference reveal that overexpression of Foxc1 transcriptionally activates the expression of Arhgap36 and dysregulates multiple facets ...

New molecular insights into the link between hepatocellular carcinoma and intratumoral fibrosis could lead to better treatment strategies, report researchers from Institute of Science Tokyo. Through a ...

Cell signaling is crucial for cells to communicate and function correctly. Disruptions in these pathways, caused by genetic mutations or environmental factors, can lead to uncontrolled cell growth, ...