One approach to overcome heterogeneity in a complex disease such as HPC is to stratify families by the presence of other primary cancers. This method is supported by evidence that some inherited ...

Amyotrophic lateral sclerosis is a progressive neurologic disorder that commonly results in paralysis and death. Despite more than a century of research, no cause of, cure for, or means of preventing ...

Despite growing interest in the use of transmission/disequilibrium test (TDT)-type analysis in association studies, there has been surprisingly scant attention paid ...