Scientists studying lipids—the fatty molecules that store energy, make up cell membranes and act as signals—produce enormous amounts of information. A single experiment can detect thousands of ...

A new single-protein analysis technique gives researchers an unprecedented ability to study proteins called scramblases, ...

The structure and function of membrane proteins depend on their interactions with lipids that constitute membranes. Actinoporins are α-pore-forming proteins that bind preferentially to ...

The body has to clear away dead cells and other unnecessary or unneeded stuff, and one mechanism that is crucial to the degradation of such materials is called LC3-associated phagocytosis (LAP). This ...

Cells throughout the human body become less efficient with age, and a newly published study points to a specific lipid, ...

Different types of lipid molecule are transported around the cell by lipid-transfer proteins. Biochemical approaches have been adapted to measure which lipids are captured by the more than 130 known ...

A new single-protein analysis technique gives researchers an unprecedented ability to study proteins called scramblases, ...

Cancer cells seldom start off stealthy. Quite to the contrary, they announce their presence to the immune system by planting chemical red flags right on their membranes. Once alerted, the body's ...

A new microfluidic method preserves worm anatomy to link lipid signals with body structure using mass spectrometry imaging. Understanding how fat molecules are distributed and function in living ...

Just as a chef perfects a dish by experimenting with flavors and textures, the researchers used an iterative process, testing variations to find the ideal structure for the ionizable lipid. This lipid ...

Tiny fat bubbles carrying gene therapy have successfully repaired DNA in the lungs and liver of animals with alpha-1 antitrypsin deficiency—a promising leap toward treating humans with this rare ...