Liquid-liquid phase separation is not a precursor to formation of amyloid fibrils, a pathological hallmark of Parkinson's disease, shows study. Rather, the formation of protein into liquid droplets ...

LLPS as a rising molecular entity in the cytoplasm regulates diseases progression via a variety of ways. For example, the relationship between LLPS and cancer can be summarized into six aspects: gene ...

Chemidroplet is a chemical tool, that fused the BTB-containing domain to the multivalent DNA binding domain (DBD) and intrinsically disordered regions (IDRs) to readily control the LLPS of these ...

Princeton bioengineer Clifford Brangwynne has been named a 2025 Keio Medical Science Prize Laureate for his discovery of liquid-liquid phase separation in cells. Japan’s Keio University awards the ...

All living organisms are made of cells, which are the smallest unit of life. Plants and animals have up to trillions of cells that work together to produce ever more intricate organization and ...