The immune system relies on a fine-tuned balance between the generation of peptide antigens and their presentation to cytotoxic T cells via Major Histocompatibility Complex (MHC) class I molecules.

Cattle possess a remarkable genetic diversity that underpins their adaptive immune responses and overall health. Central to this are the molecules encoded by the major histocompatibility complex (MHC) ...

Major histocompatibility complex class II (MHC-II) molecules play a critical, yet historically overlooked, role in tumor immunity. This review synthesizes emerging mechanistic evidence showing that ...

The major histocompatibility complex (MHC) region plays a crucial role in immune function; therefore, any genetic or epigenetic polymorphisms within the MHC locus may result in various diseases, as ...