Pretzel Therapeutics is advancing its mitochondrial disease therapies, pushing lead candidate PX578 through Phase 1 trials ...
Metabolic syndrome refers to having multiple conditions that increase the risk of health problems like diabetes, stroke and heart disease.Photograph: koto_feja/Getty Images Metabolic syndrome refers ...
The first healthy volunteers have been dosed in an early clinical trial testing NRG5051, a disease-modifying therapy for ALS ...
Mitochondrial dysfunction is associated with various chronic diseases and cancers, including neurodegenerative diseases and ...
Management of mitochondrial-related heart disease relies on multidisciplinary care and symptom control, as targeted gene-editing therapies are limited.
Prof. Ciro Leonardo Pierri's expertise in structural biology, mitochondrial carrier modeling, and drug targeting—demonstrated ...
New Review Integrates Human, Animal, and Cellular Evidence to Reframe AD as a Triad-Centered Disorder Alzheimer’s disease (AD ...
Reduction in mitochondrial activity in multiple sclerosis contributes to Purkinje cell loss. Researchers at the University of California, Riverside (CA, USA) have demonstrated the role mitochondrial ...
Mitochondrial respiratory complexes (Complexes I–V) and their assembly into respiratory supercomplexes (SCs) are fundamental to liver bioenergetics, redox homeostasis, and metabolic adaptability.
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