One of the most challenging moments in cancer treatment comes when a therapy stops working. In many metastatic cancers, drugs ...

Identifying and classifying gene mutations—which are the permanent changes in a person's DNA genetic code—are critical in better understanding, and with research, eventually treating or preventing, ...

The U.S. Food and Drug Administration has granted regular approval to treatment with Rubraca (rucaparib) for the treatment of adults with a deleterious BRCA mutation (germline and/or ...

A study of three genes associated with the development of prostate cancer found that men with inherited mutations in these genes are more likely to develop aggressive forms of the disease and die from ...

Please provide your email address to receive an email when new articles are posted on . Black men with prostate cancer had significantly greater odds of having alterations in immunotherapy targets ...

A study of men with a family history of prostate cancer has discovered an inherited form of prostate cancer. The inherited mutated gene WNT9B, which functions normally in embryonic prostate ...

The discovery shifts the paradigm from outsmarting cancer’s adaptations to exploiting them. By crowdsourcing resistance ...

An international team of researchers has discovered a new method to fight cancers that no longer respond to treatment.

A new study from the University of Michigan Rogel Health Cancer Center, published in Science, sheds light on how two distinct classes of mutations in the FOXA1 gene—commonly altered in prostate cancer ...