Excluding systematic biopsy in favor of MRI-targeted biopsy in men with elevated prostate-specific antigen (PSA) levels reduced the probability of detecting clinically insignificant cancers, but at ...

Omitting systematic biopsy in men with elevated prostate-specific antigen (PSA) levels and negative MRI results, and performing only targeted biopsy of MRI-positive lesions, eliminated more than half ...

The MRI-based prostate biopsy risk stratification tools with the greatest accuracy were the RPCRC-MRI and PLUM models Among MRI-based risk calculators for prostate biopsy, 2 models provide more ...

MRI should be considered an adjunct to, and not a replacement for, biopsies for men on active surveillance for prostate cancer. MRI does not consistently rule out the presence of Gleason grade group 2 ...

Screening for prostate cancer is burdened by a high rate of overdiagnosis. The most appropriate algorithm for population-based screening is unknown. We invited 37,887 men who were 50 to 60 years of ...

The use of 12-core systematic prostate biopsy is associated with diagnostic inaccuracy that contributes to both overdiagnosis and underdiagnosis of prostate cancer. Biopsies performed with magnetic ...

In a new health technology assessment, the U.K. National Institute for Health and Care Excellence (NICE) has voiced misgivings about the evidence behind the use of MRI/ultrasound fusion systems to ...

Abbreviated biparametric MRI was noninferior to full multiparametric MRI in detecting clinically significant prostate cancer in the prospective PRIME study, suggesting that it could become the new ...

MRI-invisible prostate lesions. It sounds like the stuff of science fiction and fantasy, a creation from the minds of H.G. Wells, who wrote The Invisible Man, or J.K. Rowling, who authored the Harry ...

For men with elevated prostate-specific antigen (PSA) levels who are at average risk for prostate cancer, evaluating suspicious lesions with MRI-directed targeted biopsy instead of systematic biopsy ...