Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease with no cure and limited treatment options.

Orphan Drug Designation applies to approximately 50,000 Patients who predominantly suffer from severe chronic pain due ...

By Vijay Kumar Malesu New mouse data reveal that ageing neurons struggle to clear synaptic proteins, shifting the burden to ...

Working with week-old zebrafish larva, researchers decoded how the connections formed by a network of neurons in the brainstem guide the fishes' gaze. The study found that a simplified artificial ...

A study of nematodes by researchers at Nagoya University in Japan has found that aging-related decline in brain function is caused by the excessive activation of certain neurons over time, rather than ...

Scientists identify a "master regulator" that may reset Brain Aging by controlling tau and gene expression in neurons.

Infection with the neurotropic pathogen Toxoplasma gondii induced release of extracellular vesicles (EVs) with microRNAs ...

Synaptic transmission is an energy hog. It requires neurons to tap ATP reserves to respond to incoming signals. How do they pull this off, thousands to millions of times per day? A new study ...

In the 1950s, advances in microscopy techniques allowed scientists to visualize synaptic communication between two brain cells for the first time. 1,2 However, many details beyond the general synapse ...