Kv7.2/7.3 channels are voltage-gated potassium channels involved in regulating membrane potential and neuronal excitability.

Neural excitability is not constant; it depends on the brain's internal state. Our results show that even identical neurons can respond differently depending on the time of day, governed by molecules ...

Ovid Therapeutics receives a "Hold" rating as it pivots pipeline focus after soticlestat trial failures in rare epileptic syndromes. OVID reported positive phase 1 results for OV329, a next-generation ...

Fixing the balance of a single brain circuit erased anxiety and social deficits in mice, revealing a powerful new target for ...

This study investigates neurophysiological mechanisms underlying corticospinal excitability and sensorimotor cortical activity in response to neuroplasticity-priming interventions. We use non-invasive ...

Nocturnal rats are active at night and accumulate fatigue toward dawn. Using optogenetic stimulation of cortical neurons and simultaneous local field potential (LFP) recordings, the study revealed ...

This exploratory study in healthy young adults found that plasma sodium levels within the normal clinical range are ...

New research provides evidence that the brain’s ability to process signals and adapt to new information fluctuates rhythmically over a 24-hour cycle. A study published inNeuroscience Research reveals ...

BIRMINGHAM, Ala. – Cocaine, a drug of abuse, activates just a portion — 10 to 20 percent — of the neurons in the brain’s nucleus accumbens, a critical region linked to motivation and addiction. Though ...