Nanowerk

Nucleic Acids: The Building Blocks of Life

Nucleic acids are complex biological molecules that store and transmit genetic information in all living organisms. They are essential for the survival and reproduction of life on Earth. The two main ...
Science Daily

Researchers take inspiration from viruses to improve delivery of nucleic acid-based therapies to cancer cells

A researcher is developing a patent-pending platform technology called LENN that mimics the dual-layer structure of viruses to deliver nucleic acid (NA)-based therapies to targeted cancer cells. A ...
GEN

Techniques to Detect Unusual Nucleic Acid Structures

Guanine quadruplexes (G-quadruplexes or G4s) are unusual nucleic acid structures with distinct biological and chemical functions. They have occupied significant attention in the nucleic acid world ...
News Medical

Complex interactions between nucleic acid sensors and enzymes in immune cells explained

Adenosine deaminase 2 (ADA2) has been identified as a regulator of toll-like receptor 9 (TLR9) activation in response to nucleic acids, according to a recent study. ADA2, previously known for its role ...
Nature

Nucleic Acid Structure and Function

"The importance of deoxyribonucleic acid (DNA) within living cells is undisputed" (Watson & Crick, 1953). This opening sentence of James Watson and Francis Crick's second major paper, published ...
Open Access Government

Unusual DNA structures and misfolded proteins

Alan Herbert, Founder and President of InsideOutBio, discusses the evolution of biological concepts related to DNA and protein structures ...
Medical Xpress

Nucleic Acid, Nucleoside, or Nucleotide:

Researchers from Geneseeq and a network of Chinese academic hospitals have validated a blood test that can detect a broad range of cancers with high accuracy using cell-free DNA. A multi-cancer early ...
C&EN

Peptide nucleic acids progress for gene editing and antisense drugs

DNA is the poster child for high-specificity binding. As long as their base sequences match, two complementary strands of DNA can navigate through a sea of biomolecules, find each other, and hold fast ...
BioWorld

Encapsulated nucleic acid therapy shows promise for sickle cell disease

Encapsulated nucleic acid therapy shows promise for sickle cell disease Jan. 26, 2024 ...
ascopubs.org

Combining cell-free RNA (cfRNA) with cell-free total nucleic acid (cfTNA) as a new paradigm for liquid biopsy.

Cell-free RNA in liquid biopsy and biomarkers profiling of hematologic and solid tumors. This is an ASCO Meeting Abstract from the 2022 ASCO Annual Meeting I. This abstract does not include a full ...
Purdue University

Purdue researchers take inspiration from viruses to improve delivery of nucleic acid-based therapies to cancer cells

WEST LAFAYETTE, Ind. — A researcher in Purdue University’s College of Science is developing a patent-pending platform technology that mimics the dual-layer structure of viruses to deliver nucleic acid ...