Pathogen adaptation occurs when novel variants gain greater fitness in the current environment than their predecessors. Host immunity, whether vaccination- or infection-induced, could shape the ...

A parasite which has devastating impacts on agriculture and human health is the first pathogen to have its proteins located and mapped within its cells -- providing clues to their function and helping ...

Heterogeneity is ubiquitous in real-world host populations, yet most theories assume homogeneity. Using a metapopulation model, we examine how host heterogeneities, such as uneven movement patterns ...

Evolution of bacterial pathogen populations has been detected in a variety of ways including phenotypic tests, such as metabolic activity, reaction to antisera and drug resistance and genotypic tests ...

Combining genomic data and human travel patterns over a 14-year period in South Africa reveals key insights into the spread, evolution and resistance patterns of a major bacterium behind pneumonia and ...

The rapid identification and genomic analysis of zoonotic pathogens are critical for safeguarding public health and controlling outbreaks. PathoBase, an advanced computational platform, provides a ...

Antimicrobial resistance frequently carries a fitness cost to a pathogen, measured as a reduction in growth rate compared to the sensitive wildtype, in the absence of antibiotics. Existing empirical ...

This is a preview. Log in through your library . Abstract Immune memory evolved to protect hosts from reinfection, but incomplete responses that allow future reinfection may inadvertently select for ...

Acid rain from fossil fuel pollution may be quietly training soil bacteria to become longer-lived, more transmissible, and more deadly, according to a new study in the journal New Contaminants that ...