Protein drugs feature significant advantages over small molecule therapeutics, including low toxicity, high specificity, and development speed. However, the quality control requirements are ...

Proteins play a key role in the life sciences - from basic research and biotechnological applications to the development and manufacturing of pharmaceuticals. Scientists at the Technical University of ...

Researchers have developed a method to evaluate the folding stability of a million proteins simultaneously. DNA libraries were used to generate protein -- DNA complexes that were treated with enzymes ...

An innovative machine learning approach has been shown to rapidly predict multiple protein configurations. A new paper presents the method that predicts the relative populations of protein ...

Understanding the structure of proteins is critical for demystifying their functions and developing drugs that target them. To that end, a team of researchers at Brown University has developed a way ...

In a paper recently published in Nature Communications, the HUN-REN-ELTE Protein Modeling Research Group (Institute of Chemistry) has laid the foundations for a mathematical method, allowing the ...

Proteins are made of chains of amino acids, and a basic tenet of biology is that the sequence of amino acids determines how a protein folds into a 3D shape which, in turn, dictates the protein’s ...

Drug discovery requires two separate steps: checking whether a drug can bind to a harmful molecule or its receptor, and ...