A research team at The University of Osaka revealed that the loss of heterochromatin can cause a chain reaction leading to ...

Osaka, Japan – Changes in genes have been linked to the development of different diseases for a while. However, it's not ...

A look at neurodegenerative disease in the context of the aging brain will test the link between peculiar genomic structures in the cells, called R-loops, known to cause DNA damage as we age and ...

“There are currently limited therapeutic options for elderly patients with myeloid malignancies, who are ineligible for stem cell transplantation,” commented Dr. Sayantani Sinha, a postdoctoral ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 119, No. 50 (December 13, 2022), pp. 1-12 (12 pages) R-loops, or RNA:DNA hybrids, can induce DNA damage, which ...