The publication of a study in Nature this week (August 15)—combined with a similar study in Science earlier this month (August 5)—could force a reexamination of how RNA interference (RNAi) works, said ...

The fledgling science of RNAi is making strides to take its place not only as a powerful therapeutic but also as a dynamic tool to increase the speed and efficiency of target validation and drug ...

ARLINGTON, Texas — A UT-Arlington biologist is leading a $1.8 million federally funded project to study the molecular processes affecting gene regulation to better understand how small genetic ...

Historically, most therapeutics have been small chemicals and antibodies designed to target cellular proteins. New kinds of therapeutics are emerging, however, from a better understanding of noncoding ...

Researchers at Indiana University Bloomington have uncovered previously hidden steps of a gene silencing process used to combat viruses and other would-be genome invaders. The new findings, published ...

Arrowhead Pharmaceuticals’ phase 1/2a study has found the company’s investigational RNA interference (RNAi) candidate was generally well tolerated among 14 patients with kidney disease. The “select” ...

In a recent study posted to the bioRxiv* preprint server, researchers identified a novel antiviral pathway different from the interferon (IFN) pathway that inhibited poxvirus(es) replication. Study: A ...