I. Platinum-based therapies induce DNA inter-strand crosslinks (ICLs), which exacerbate genomic instability and impede DNA replication. In BRCA1/2-deficient tumor cells, the repair of these DNA ...
Homologous recombination is a DNA repair mechanism that counteracts double-stranded breaks in DNA. Researchers at Kindai University have recently revealed how the Sae2 protein coordinates with the ...
Comparative effectiveness of cabazitaxel (C) vs. lutetium Lu-177 vipivotide tetraxetan (Lu) in patients (pts) with metastatic castration-resistant prostate cancer (mCRPC). Assessment of PSMA PET/CT ...
Research shows that the breast cancer gene 1 (BRCA1) not only pushes accurate DNA repair to guard against cancer but promotes subsequent activity in tumor suppression. A new study led by The ...
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