Transforming growth factor-beta (TGF-β), a well-known morphogen, is recognized for its role in regulating growth and development. The study is published in the journal Nature Communications. The ...

Transforming growth factor beta (TGF-β) encompasses a family of three related cytokines that orchestrate the cellular and molecular events of wound repair. Upon injury, TGF-β is released from ...

Bone remodelling is a dynamic process that balances resorption and formation to preserve skeletal integrity. Transforming growth factor beta (TGF-β) comprises a family of secreted cytokines that ...

For years, scientists have thought that TGF-Beta, a signaling protein that holds sway over an astonishing array of cellular processes from embryonic development to cancer, could only do its work once ...

Liver fibrosis, a pathological scarring process resulting from chronic liver injury, represents a significant global health burden due to its potential progression to cirrhosis and hepatocellular ...

Suppression of the TGF-β/Smad pathway via a Smad7/Smurf2-dependent ubiquitination mechanism, and direct disruption of the apoptosis-resistant barrier in HSCs. This work extends the role of CTSK beyond ...

HO-1 inhibits the activation of the TGF-ß/Smad3 pathway in NAFLD-related liver fibrosis through SIRT1. These findings provide insights into new therapeutic strategies for treating NAFLD-associated ...

We're going to get started. Thank you, everyone, for joining us here in Berlin, and there are many more of you that are online. Welcome to the solid tumor update that we're having at ESMO 2025. We're ...

BPC-157 and TB-500, originating from gastric and thymic sources respectively, both influence angiogenesis, cytoskeletal ...