Lower estimated tubular secretion was found to be associated with a faster decline of estimated glomerular filtration rate (eGFR) but wasn’t associated with progression of chronic kidney disease or ...
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Autophagy and lysosomal pathways orchestrate unconventional secretion of Parkinson's disease protein
Intracellular protein trafficking and secretion of proteins into the extracellular environment are sequential and tightly regulated processes in eukaryotic cells. Conventionally, proteins that are ...
Cells have sophisticated methods of sensing stimuli and communicating with nearby cells in response to these stimuli. For example, macrophages can sense environmental stimuli—tissue damage, foreign ...
Intracellular protein trafficking and secretion of proteins into the extracellular environment are sequential and tightly regulated processes in eukaryotic cells. Conventionally, proteins that are ...
Autophagy and lysosomal pathways orchestrate unconventional secretion of Parkinson’s disease protein
Oxidative stress induced by 6-OHDA stimulates autophagy flux, which enhances STX17-mediated autolysosome formation, leading to the degradation of autophagosomal contents. However, in response to ...
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