A case study reviews the reformulation and scale up of high drug load prototype using wet granulation process for a model formulation. The reformulation of a 100-mg tablet into a 300-mgtablet ...

Adopting a Quality by Design (QbD) approach for wet granulation requires manufacturers to comprehend the correlation between process variables, such as powder characteristics and equipment ...

In dry granulation, powders bind because of the application of mechanical stress. As particles are forced to be within closer proximity, entrained air is forced out, bulk density increases, and a ...

Wet granulation is the most widely-used technology for granulation, even though it consists of many steps and product transfer, which increases production costs. It is the most flexible granulation ...

Pharmaceutical research and development (R&D) and industry require a continuous fluid-bed dryer that provides a lengthy process time and delivers a high standard for a long time. This article ...

Granulation is a critical unit operation in pharmaceutical manufacturing, where fine powders are agglomerated into granules to improve flow properties, uniformity, and compaction performance. The ...

Troy, Alabama-based KW Plastics is a large recycler of postconsumer high-density polyethylene (HDPE), polypropylene (PP) and other scrap materials. The company also produces products made of ...

Granulation is important in the pharmaceutical industry because of increased pressures due to the costs of manufacturing solid dosage forms. Granulation forms coarser collections from fine powder.